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XNAS • Healthcare

Ionis Pharmaceuticals, Inc. (IONS)

PHARMACEUTICAL PREPARATIONS · 2855 GAZELLE COURT, CARLSBAD, CA, 92010

XNASstockActive listing
44.38
+1.44 (+3.35%)
Quote updated 10/19/2026, 4:00:00 AM
Previous close42.94
Open43.33
Day range43.00 – 44.54
52-week range42.08 – 86.74
Volume3,098,988
Market cap7.52B
PRICE HISTORY

Stock price history and performance

Daily closing prices from the stored market history.

250 sessions
$90$77$64$52$39Oct 21Apr 21Oct 19
STOCK RESEARCH · EDITORIAL ANALYSIS

Ionis Pharmaceuticals, Inc. (IONS): Investment Research & Business Outlook

A research-led explanation of the company, its financial evidence, valuation context and risks—not just a list of market numbers.

Research note

What the available evidence tells us

The latest stored quote for Ionis Pharmaceuticals, Inc. (IONS) is 44.38, timestamped 10/19/2026, 4:00:00 AM. A quote is a point-in-time observation; it does not, by itself, explain why the price moved or establish whether the shares are attractive.

Business and financial quality

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases. Ionis and Biogen brought Spinraza to market in 2016 as a treatment for spinal muscular atrophy, and Biogen launched ALS drug Qalsody in 2023. Ionis brought two additional drugs to market via its cardiovascular-focused subsidiary Akcea, including ATTR amyloidosis drug Tegsedi (2018) and cardiology drug Waylivra (Europe, 2019). Ionis and AstraZeneca launched polyneuropathy drug Wainua in 2024. Ionis marked its first two independent launches in 2025 for Tryngolza (for FCS) and Dawnzera (for HAE). Stored fundamentals include 34 usable headline metrics. These should be read across several reporting periods and compared with peers before drawing a conclusion about business quality.

Valuation: context matters

The stored trailing P/E ratio is 23.83. P/E compares a company’s share price with its earnings, but it should be interpreted alongside expected growth, earnings quality, cyclicality and comparable companies.

Price trend and quantitative outlook

The chart is based on 250 stored daily price observations. Historical performance describes what happened over that period; it is not a guarantee of future returns. The current stored quantitative model signal is “neutral”. Treat model outputs as scenarios with uncertainty, not as certain targets or personalized advice.

Key risks and what to watch next

Risk records exist for this company; review the risk and performance section below for the available volatility, drawdown and risk-adjusted measures. The next useful evidence to review is the company’s next reported financial results, changes in forward estimates, and primary-source disclosures.

Editorial integrity: this summary uses fields available in the current database. Missing evidence is called out rather than filled with invented facts.

What the numbers mean for investors

Business quality

A reliable revenue-growth reading is not available or is not positive in the latest stored snapshot. Review multiple reporting periods before judging the growth trajectory.

Profitability

Gross margin is +0.00% and operating margin is -38.18%. The gap helps show how much operating costs absorb after direct costs; compare the trend with prior periods and sector peers.

Valuation

The stored P/E is 23.83. A multiple is not a verdict by itself: interpret it alongside expected earnings growth, cyclicality, cash flow, and comparable companies.

Price trend

The latest quote can be compared with the 20-, 50- and 200-day moving averages (44.10, 51.48, and 68.43). Moving averages describe trend, not intrinsic value, and can lag sudden market changes.

Bull case, bear case and evidence to watch

Bull case

The bullish case needs confirmation from reported revenue growth, cash generation, and future company disclosures; the current snapshot does not establish those conditions together.

Bear case

Potential downside still includes weaker demand, margin compression, competition, execution issues, or a broad market sell-off. Company-specific evidence is needed to quantify these risks.

What to watch next

Track the next earnings release, changes in revenue and margin trends, cash flow, management guidance, analyst estimate revisions, and primary-source filings. Update the thesis when new evidence arrives rather than relying on one ratio or forecast.

These interpretations are rule-based explanations of the stored fields, not independently verified company-specific forecasts. Missing data is not treated as zero; all investment cases remain conditional on new evidence.

US Market AI Research Desk · Data/research timestamp: Oct 19, 2026 · Methodology & disclaimer
QUANTITATIVE RESEARCH

Stock forecast and analysis: price outlook

Forecasts are model outputs, not promises or personalized investment advice.

neutral
HorizonModel targetExpected changeSignalConfidence score
24H44.10-0.64%neutral80
7D43.32-2.39%bearish80
30D41.54-6.41%bearish80
90D38.78-12.61%bearish80

Long-term model scenarios

Latest stored scenario per future target year. Bear, base and bull prices are model scenarios, not guaranteed targets. The relative model score is not a calibrated probability; uncertainty rises materially for distant years.

Target yearBase caseBear caseBull caseExpected CAGRRelative model scoreSignal
202745.9345.8546.004%72long-term-positive
203051.6650.5052.844%71long-term-positive
203562.8557.5568.584%70long-term-positive
204076.4764.6690.274%67long-term-positive
2050113.2081.28156.934%63long-term-positive
COMPANY FUNDAMENTALS

Financial performance and company fundamentals

Reported fields from the current fundamentals snapshot.

Revenue267.95MTotal sales reported for the period; compare growth across several periods.
Revenue growth-40.73%How quickly sales are expanding or contracting versus the comparison period.
Gross profit0Interpret alongside the company’s history, sector peers, reporting period and data source.
Operating income-102.29MInterpret alongside the company’s history, sector peers, reporting period and data source.
Net income-114.65MInterpret alongside the company’s history, sector peers, reporting period and data source.
EPS (reported period)-0.69Earnings per share for the stored reporting period; confirm whether the figure is quarterly, annual or trailing twelve months before comparing it with valuation multiples.
EPS growth-198.57%Interpret alongside the company’s history, sector peers, reporting period and data source.
Gross margin+0.00%Share of revenue left after direct costs; higher margins can indicate pricing power.
Operating margin-38.18%Share of revenue left after operating expenses, before interest and taxes.
Net margin-42.79%Share of revenue that remains as profit after expenses and taxes.
EBITDA-211.62MInterpret alongside the company’s history, sector peers, reporting period and data source.
EBIT-102.29MInterpret alongside the company’s history, sector peers, reporting period and data source.
Cash & equivalents350.07MInterpret alongside the company’s history, sector peers, reporting period and data source.
Total assets2.99BInterpret alongside the company’s history, sector peers, reporting period and data source.
Total liabilities2.55BInterpret alongside the company’s history, sector peers, reporting period and data source.
Total debt0Interpret alongside the company’s history, sector peers, reporting period and data source.
Shareholders equity439.74MInterpret alongside the company’s history, sector peers, reporting period and data source.
Current assets2.49BInterpret alongside the company’s history, sector peers, reporting period and data source.
Current liabilities315.64MInterpret alongside the company’s history, sector peers, reporting period and data source.
Operating cash flow565.53MInterpret alongside the company’s history, sector peers, reporting period and data source.
Capital expenditure16.08MInterpret alongside the company’s history, sector peers, reporting period and data source.
Free cash flow549.45MCash remaining after operating needs and capital expenditure; can support investment or shareholder returns.
FCF margin+205.06%Interpret alongside the company’s history, sector peers, reporting period and data source.
Return on equity-26.07%Profit generated relative to book equity; leverage and one-off gains can distort it.
Return on assets-3.83%Interpret alongside the company’s history, sector peers, reporting period and data source.
Debt / equity0Debt relative to shareholder equity; definitions may vary by data provider.
Price / sales26.73Interpret alongside the company’s history, sector peers, reporting period and data source.
Price / book16.29Interpret alongside the company’s history, sector peers, reporting period and data source.
EV / revenue26.65Interpret alongside the company’s history, sector peers, reporting period and data source.
Price / FCF13.72Interpret alongside the company’s history, sector peers, reporting period and data source.
Earnings yield-1.59%Interpret alongside the company’s history, sector peers, reporting period and data source.
Shares outstanding165,419,000Interpret alongside the company’s history, sector peers, reporting period and data source.
Book value / share2.66Interpret alongside the company’s history, sector peers, reporting period and data source.
FCF / share3.32Interpret alongside the company’s history, sector peers, reporting period and data source.
Market cap7.52BMarket value of outstanding shares, not the same as enterprise value.
P/E ratio23.83Share price relative to earnings per share; interpret alongside growth and peers.
52-week high86.74Highest stored price over the rolling year; not a fair-value estimate.
52-week low42.08Lowest stored price over the rolling year; not a support guarantee.
Average volume3,098,988Typical shares traded; helps assess liquidity but can change around events.
TECHNICALS

Technical indicators

Latest stored daily indicator snapshot; unavailable indicators are omitted.

Oct 20, 2026
RSI (14)43.47Momentum oscillator from 0–100; extreme readings are context, not automatic buy/sell signals.
SMA 2044.10Average closing price over about 20 trading sessions; a short-term trend reference.
SMA 5051.48Average closing price over about 50 sessions; often used to assess medium-term direction.
SMA 10059.42Interpret alongside the company’s history, sector peers, reporting period and data source.
SMA 20068.43Average closing price over about 200 sessions; a longer-term trend reference.
EMA 2045.07Interpret alongside the company’s history, sector peers, reporting period and data source.
EMA 5050.18Interpret alongside the company’s history, sector peers, reporting period and data source.
EMA 20062.92Interpret alongside the company’s history, sector peers, reporting period and data source.
MACD-2.11Interpret alongside the company’s history, sector peers, reporting period and data source.
MACD signal-2.61Interpret alongside the company’s history, sector peers, reporting period and data source.
MACD histogram0.5Difference between MACD and its signal line; sign and changes indicate momentum shifts.
Bollinger upper46.00Interpret alongside the company’s history, sector peers, reporting period and data source.
Bollinger middle44.10Interpret alongside the company’s history, sector peers, reporting period and data source.
Bollinger lower42.21Interpret alongside the company’s history, sector peers, reporting period and data source.
Stochastic55.22Interpret alongside the company’s history, sector peers, reporting period and data source.
Stochastic signal38.92965352758496Interpret alongside the company’s history, sector peers, reporting period and data source.
Williams %R-44.78Interpret alongside the company’s history, sector peers, reporting period and data source.
CCI-21.41Interpret alongside the company’s history, sector peers, reporting period and data source.
MFI41.95Interpret alongside the company’s history, sector peers, reporting period and data source.
ROC+0.86%Interpret alongside the company’s history, sector peers, reporting period and data source.
OBV-13.15MInterpret alongside the company’s history, sector peers, reporting period and data source.
Momentum2.02Interpret alongside the company’s history, sector peers, reporting period and data source.
Volatility+38.28%Interpret alongside the company’s history, sector peers, reporting period and data source.
ATR1.58Average true range estimates recent price movement size, not direction.
ADX24.1Measures trend strength, not whether the trend is bullish or bearish.
Support level42.08Interpret alongside the company’s history, sector peers, reporting period and data source.
Resistance level46.95Interpret alongside the company’s history, sector peers, reporting period and data source.
TrendbearishInterpret alongside the company’s history, sector peers, reporting period and data source.
REPORTED RESULTS

Financial statements, earnings history and estimate revisions

Recent normalized financial statement records.

Showing up to 60 recent statement records. Reported periods and statement types are preserved; blank values are not estimated. Contradictory zero sentinels are withheld instead of presented as verified facts.

PeriodStatementFiscal periodBasisRevenueCost of revenueGross profitOperating incomeNet incomeBasic EPSDiluted EPSCashTotal assetsTotal liabilitiesDebtEquityOperating cash flowCapexFree cash flowSource
Jun 30, 2026balance sheetFY-2026-Q2quarterly———————350.07M2.99B2.55B0439.74M———3spread
Jun 30, 2026cash flowFY-2026-Q2annual————————————-227.29M37.84M-265.13M3spread
Jun 30, 2026cash flowFY-2026-Q2quarterly————————————565.53M16.08M549.45M3spread
Jun 30, 2026income statementFY-2026-Q2quarterly267.95M—0-102.29M-114.65M-0.69-0.69————————3spread
Jun 30, 2026income statementFY-2026-Q2annual514.04M-5.72M0-219.71M-207.17M-1.25-1.25————————3spread
Mar 31, 2026balance sheetFY-2026-Q1quarterly———————173.38M2.82B3.59B0491.41M———3spread
Mar 31, 2026cash flowFY-2026-Q1quarterly————————————-792.82M21.76M-814.58M3spread
Mar 31, 2026income statementFY-2026-Q1quarterly246.09M—0-117.42M-92.53M-0.56-0.56————————3spread
Dec 31, 2025balance sheetFY-2025-Q4quarterly———————372.26M3.52B3.03B0489.09M———3spread
Dec 31, 2025cash flowFY-2025-Q4annual————————————-269.57M51.44M-321.01M3spread
Dec 31, 2025cash flowFY-2025-Q4quarterly————————————-137.71M21.29M-159M3spread
Dec 31, 2025income statementFY-2025-Q4annual943.71M—0-381.68M-381.39M-2.38-2.38————————3spread
Dec 31, 2025income statementFY-2025-Q4quarterly0—0-214.46M-229.39M-1.43-1.43————————3spread
Sep 30, 2025balance sheetFY-2025-Q3quarterly———————338.34M3.03B2.42B0617.97M———3spread
Sep 30, 2025cash flowFY-2025-Q3quarterly————————————-130.87M30.15M-161.03M3spread
Sep 30, 2025income statementFY-2025-Q3quarterly740.38M—0-167.23M-151.99M-0.95-0.95————————3spread
Jun 30, 2025balance sheetFY-2025-Q2quarterly———————297.3M2.99B2.35B0631.72M———3spread
Jun 30, 2025cash flowFY-2025-Q2annual————————————563K24.88M-24.32M3spread
Jun 30, 2025cash flowFY-2025-Q2quarterly————————————151.34M12.31M139.03M3spread
Jun 30, 2025income statementFY-2025-Q2quarterly452.05M—0139.82M123.55M0.780.70————————3spread
Jun 30, 2025income statementFY-2025-Q2annual583.66M—0-7.05M-23.39M-0.15-0.15————————3spread
Mar 31, 2025balance sheetFY-2025-Q1quarterly———————264.19M2.81B2.34B0475.73M———3spread
Mar 31, 2025cash flowFY-2025-Q1quarterly————————————-150.78M12.58M-163.35M3spread
Mar 31, 2025income statementFY-2025-Q1quarterly131.61M—0-146.86M-146.94M-0.93-0.93————————3spread
Dec 31, 2024balance sheetFY-2024-Q4quarterly———————242.08M3B2.42B0588.35M———3spread
Dec 31, 2024cash flowFY-2024-Q4annual————————————-503.98M45.28M-549.26M3spread
Dec 31, 2024cash flowFY-2024-Q4quarterly————————————-118.28M25.5M-143.77M3spread
Dec 31, 2024income statementFY-2024-Q4annual705.14M—0-475.08M-453.9M-3.04-3.04————————3spread
Dec 31, 2024income statementFY-2024-Q4quarterly226.58M—0-110.82M-104.35M-0.70-0.70————————3spread
Sep 30, 2024balance sheetFY-2024-Q3quarterly———————334.61M3.08B2.42B0662.47M———3spread
Sep 30, 2024cash flowFY-2024-Q3quarterly————————————-114.99M9.06M-124.05M3spread
Sep 30, 2024income statementFY-2024-Q3quarterly478.56M—0-364.26M-349.55M-2.38-2.38————————3spread
Jun 30, 2024balance sheetFY-2024-Q2quarterly———————293.99M2.69B2.43B0263.7M———3spread
Jun 30, 2024cash flowFY-2024-Q2annual————————————-269.82M10.73M-280.55M3spread
Jun 30, 2024cash flowFY-2024-Q2quarterly————————————-119.88M6.23M-126.11M3spread
Jun 30, 2024income statementFY-2024-Q2annual344.75M—0-215.6M-209.07M-1.43-1.43————————3spread
Jun 30, 2024income statementFY-2024-Q2quarterly225.25M—0-66.09M-66.27M-0.45-0.45————————3spread
Mar 31, 2024balance sheetFY-2024-Q1quarterly———————348.89M2.76B2.47B0296.52M———3spread
Mar 31, 2024cash flowFY-2024-Q1quarterly————————————-149.94M4.49M-154.43M3spread
Mar 31, 2024income statementFY-2024-Q1quarterly119.5M—0-149.51M-142.8M-0.98-0.98————————3spread
Dec 31, 2023balance sheetFY-2023-Q4quarterly———————399.27M2.99B2.6B0386.69M———3spread
Dec 31, 2023cash flowFY-2023-Q4annual————————————-309.34M23.81M-333.14M3spread
Dec 31, 2023cash flowFY-2023-Q4quarterly————————————32.87M819K32.05M3spread
Dec 31, 2023income statementFY-2023-Q4quarterly324.51M—0-6.12M-9.26M-0.06-0.06————————3spread
Dec 31, 2023income statementFY-2023-Q4annual787.65M—0-353.73M-366.29M-2.56-2.56————————3spread
Sep 30, 2023balance sheetFY-2023-Q3quarterly———————352.06M2.93B2.62B0315.46M———3spread
Sep 30, 2023cash flowFY-2023-Q3quarterly————————————-341.23M24.62M-365.85M3spread
Sep 30, 2023income statementFY-2023-Q3quarterly463.14M—0-347.61M-357.02M-2.50-2.50————————3spread
Jun 30, 2023balance sheetFY-2023-Q2quarterly———————424.79M2.97B2.54B0428.3M———3spread
Jun 30, 2023cash flowFY-2023-Q2quarterly————————————-97.49M12.01M-109.5M3spread
Jun 30, 2023cash flowFY-2023-Q2annual————————————-231.36M22.48M-253.84M3spread
Jun 30, 2023income statementFY-2023-Q2quarterly188.41M—0-90.2M-85.29M-0.60-0.60————————3spread
Jun 30, 2023income statementFY-2023-Q2annual318.94M—0-204.34M-209.61M-1.47-1.47————————3spread
Mar 31, 2023balance sheetFY-2023-Q1quarterly———————309.03M2.89B2.4B0486.57M———3spread
Mar 31, 2023cash flowFY-2023-Q1quarterly————————————-133.99M10.47M-144.46M3spread
Mar 31, 2023income statementFY-2023-Q1quarterly130.52M—0-114.15M-124.32M-0.87-0.87————————3spread
Dec 31, 2022balance sheetFY-2022-Q4quarterly———————276.47M2.53B1.96B0572.89M———3spread
Dec 31, 2022cash flowFY-2022-Q4annual————————————-274.37M15.72M-290.09M3spread
Dec 31, 2022cash flowFY-2022-Q4quarterly————————————-201.07M4.14M-205.21M3spread
Dec 31, 2022income statementFY-2022-Q4annual587.37M—0-410.19M-269.72M-1.90-1.90————————3spread

Financial metric history

PeriodRevenue growthGross marginOperating marginNet marginROEROIC
Jun 30, 2026-40.73%+0.00%-38.18%-42.79%-26.07%—

Earnings history

These are SEC-reported financial facts grouped by fiscal period. The displayed date is the SEC filing/observation date, not a verified earnings announcement or release date. Use the company’s investor-relations calendar for confirmed earnings-release timing.

SEC filing / observation dateFiscal periodEPS reportedEPS estimateRevenue reportedRevenue estimate
Jul 29, 2026Q2-0.69—267.95M—
Apr 29, 2026Q1-0.56—246.09M—
Feb 26, 2026FY-1.41—943.71M—
Oct 29, 2025Q3-0.80—156.72M—
Jul 30, 2025Q20.70———
Apr 30, 2025Q1-0.93—131.61M—
VALUATION

Stock valuation: P/E, forward P/E and multiples

Multiples shown only when the database has a usable value.

P/E ratio23.83
Price / sales26.73
Price / book16.29
Enterprise value7.14B

Peer comparisons are withheld until a comparable industry group and a reliable peer set are verified.

LATEST DEVELOPMENTS

News and company updates

Stories linked to this stock in the current database.

RISK CONTEXT

Risk and performance profile

Computed risk/performance records; not a recommendation. Mathematically uninterpretable or extreme ratios are withheld rather than displayed as reliable facts.

Volatility+51.79%
Beta0.46
ATR1.73
Maximum drawdown-49.94%
Sharpe ratio-0.81
Sortino ratio-0.69
Debt / equity0
Current ratio7.89
Interest coverage-4.92
1-day return+4.57%
5-day return+1.42%
1-month return-23.98%
3-month return-46.91%
6-month return-40.59%
YTD return-44.18%
1-year return-36.02%
All-time return+5.60%
RESEARCH EVIDENCE

Source data and research records

Expandable evidence tables keep the main page focused while preserving detailed data.

Institutional holders and ownership

Showing up to 50 recent holder records. Values failing a basic implied-price check are withheld, not silently corrected.

PeriodFiledHolderCIKSharesValueOwnershipShares changeChange %Source
Jun 30, 2026Aug 7, 2026Tweedy, Browne Co LLC7329052,280,311180.81M———SEC_13F_DATASET
Jun 30, 2026Aug 11, 2026Keating Financial Advisory Services, Inc.2103443886.98K———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026Squarepoint Ops LLC1642575109,3798.67M———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026Sixth Street Partners Management Company, L.P.18120951,605,001127.26M———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026Aster Capital Management (DIFC) Ltd204091519015.07K———SEC_13F_DATASET
Jun 30, 2026Jul 16, 2026Capital Advisors, Ltd. LLC1597878295Withheld: value fails validation———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC1638555787,26362.42M———SEC_13F_DATASET
Jun 30, 2026Jul 13, 2026Wedmont Private Capital19042746,723391.62K———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026JONES FINANCIAL COMPANIES LLLP81591747,4423.85M———SEC_13F_DATASET
Jun 30, 2026Aug 12, 2026BESSEMER GROUP INC105407494Withheld: value fails validation———SEC_13F_DATASET
Jun 30, 2026Aug 12, 2026Capital World Investors142284921,669,2261.72B———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026Federation des caisses Desjardins du Quebec2022297604.76K———SEC_13F_DATASET
Jun 30, 2026Jul 10, 2026Handelsbanken Fonder AB1398318383,211Withheld: value fails validation———SEC_13F_DATASET
Jun 30, 2026Aug 7, 2026SG Americas Securities, LLC131336074,589Withheld: value fails validation———SEC_13F_DATASET
Jun 30, 2026Aug 12, 2026Inspire Investing, LLC16701398,127644.39K———SEC_13F_DATASET
Jun 30, 2026Aug 13, 2026ALGERT GLOBAL LLC1275218206,85316.4M———SEC_13F_DATASET
Jun 30, 2026Aug 4, 2026State of New Jersey Common Pension Fund D148306650,7434.02M———SEC_13F_DATASET
Jun 30, 2026Aug 13, 2026VANGUARD ASSET MANAGEMENT, Ltd1680208155,08812.3M———SEC_13F_DATASET
Jun 30, 2026Aug 13, 2026Dynasty Wealth Management, LLC172759913,6611.08M———SEC_13F_DATASET
Jun 30, 2026Aug 3, 2026OPPENHEIMER ASSET MANAGEMENT INC.126911911,157884.64K———SEC_13F_DATASET
Jun 30, 2026Aug 13, 2026One Capital Management, LLC160658858,9394.43M———SEC_13F_DATASET
Jun 30, 2026Aug 7, 2026Privium Fund Management B.V.1795097319,92425.37M———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026OSAIC HOLDINGS, INC.167704450740.2K———SEC_13F_DATASET
Jun 30, 2026Aug 3, 2026Vontobel Holding Ltd.15883404,957393.04K———SEC_13F_DATASET
Jun 30, 2026Aug 3, 2026CIBC Asset Management Inc10219265,017397.8K———SEC_13F_DATASET
Jun 30, 2026Aug 6, 2026SouthState Bank Corp764038141.11K———SEC_13F_DATASET
Jun 30, 2026Aug 7, 2026ARIZONA STATE RETIREMENT SYSTEM155848143,3023.43M———SEC_13F_DATASET
Jun 30, 2026Jul 1, 2026EASTERN BANK112639530023.79K———SEC_13F_DATASET
Jun 30, 2026Aug 13, 2026Dana Investment Advisors, Inc.142751423,2721.85M———SEC_13F_DATASET
Jun 30, 2026Aug 3, 2026Raiffeisen Bank International AG204488535,0002.82M———SEC_13F_DATASET
Jun 30, 2026Aug 7, 2026GF FUND MANAGEMENT CO. LTD.20570603,497277.28K———SEC_13F_DATASET
Jun 30, 2026Aug 13, 2026Horizon Investments, LLC1560717262.06K———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026Graham Capital Management, L.P.131542116,7171.33M———SEC_13F_DATASET
Jun 30, 2026Aug 11, 2026Stratos Wealth Partners, LTD.16128657,801618.54K———SEC_13F_DATASET
Jun 30, 2026Aug 7, 2026Mitsubishi UFJ Asset Management Co., Ltd.14665462,618207.58K———SEC_13F_DATASET
Jun 30, 2026Aug 13, 2026SCHRODER INVESTMENT MANAGEMENT GROUP108661957,7224.66M———SEC_13F_DATASET
Jun 30, 2026Aug 11, 2026ProShare Advisors LLC13579555,417429.51K———SEC_13F_DATASET
Jun 30, 2026Jul 23, 2026KOM Wealth Management Group, LLC18041162,654210.44K———SEC_13F_DATASET
Jun 30, 2026Aug 13, 2026ODDO BHF ASSET MANAGEMENT SAS1686970274426.79K———SEC_13F_DATASET
Jun 30, 2026Aug 11, 2026HORIZON KINETICS ASSET MANAGEMENT LLC105682310,904864.58K———SEC_13F_DATASET
Jun 30, 2026Aug 11, 2026Orion Investment Co2033920220,33517.47M———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026Basecamp Wealth Advisors LLC2115254987.77K———SEC_13F_DATASET
Jun 30, 2026Aug 6, 2026Global Retirement Partners, LLC17497442,282180.94K———SEC_13F_DATASET
Jun 30, 2026Jul 24, 2026Atle Fund Management AB1381843137,13110.87M———SEC_13F_DATASET
Jun 30, 2026Aug 13, 2026CAPITAL FUND MANAGEMENT S.A.1323645329,55426.13M———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026CANADA PENSION PLAN INVESTMENT BOARD128371833,3002.64M———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026BAMCO INC /NY/101791814,0001.11M———SEC_13F_DATASET
Jun 30, 2026Aug 11, 2026MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC92212731,2992.48M———SEC_13F_DATASET
Jun 30, 2026Aug 14, 2026Artia Global Partners LP1937964144,37611.45M———SEC_13F_DATASET
Jun 30, 2026Jul 22, 2026Golden State Wealth Management, LLC177603337629.81K———SEC_13F_DATASET
PeriodShares outstandingInstitutional ownershipInsider ownership
Jun 30, 2026165,419,000+363.37%—
Insider transactions

Reported transaction values and remaining holdings are shown only when supplied by the source.

Transaction dateFiledInsiderTitleTypeCodeSharesPriceReported valueShares afterFilingSource
Oct 16, 2026Oct 19, 2026Devers Shannon L.EVP, Chief Human Resources OfcSaleS1,35743.5459.08K17,811Open filingSEC_FORM_3_4_5
Oct 16, 2026Oct 19, 2026Swayze EricEVP ResearchSaleS5343.542.31K390Open filingSEC_FORM_3_4_5
Oct 15, 2026Oct 19, 2026Devers Shannon L.EVP, Chief Human Resources OfcOption ExerciseM2,8200.00019,168Open filingSEC_FORM_3_4_5
Oct 15, 2026Oct 19, 2026Swayze EricEVP ResearchOption ExerciseM1250.000443Open filingSEC_FORM_3_4_5
SEC filings

Showing up to 30 latest filings. Open the original SEC document when a URL is available.

FiledAcceptedFormDescriptionReporting periodAccessionSEC document
Oct 19, 2026—4PRIMARY DOCUMENTOct 15, 20260000874015-26-000267View filing
Oct 19, 2026—4PRIMARY DOCUMENTOct 15, 20260000874015-26-000266View filing
Oct 16, 2026—144——0000874015-26-000263View filing
Sep 23, 2026—8-KCURRENT REPORT FILINGSep 23, 20260001140361-26-037371View filing
Sep 4, 2026—8-K8-KSep 4, 20260001140361-26-035802View filing
Sep 4, 2026—8-K8-KSep 3, 20260001140361-26-035657View filing
Sep 2, 2026—4PRIMARY DOCUMENTAug 31, 20260000874015-26-000260View filing
Sep 2, 2026—4PRIMARY DOCUMENTAug 31, 20260000874015-26-000262View filing
Sep 2, 2026—4PRIMARY DOCUMENTAug 31, 20260000874015-26-000261View filing
Sep 2, 2026—4PRIMARY DOCUMENTAug 31, 20260000874015-26-000259View filing
Jul 31, 2026—4PRIMARY DOCUMENTJul 30, 20260000874015-26-000254View filing
Jul 29, 2026—10-QIONIS PHARMACEUTICALS, INC. 10-Q 06-30-2026Jun 30, 20260000874015-26-000251View filing
Jul 29, 2026—8-K8-KJul 29, 20260001140361-26-029960View filing
Jul 17, 2026—4PRIMARY DOCUMENTJul 15, 20260000874015-26-000247View filing
Jul 17, 2026—4PRIMARY DOCUMENTJul 15, 20260000874015-26-000246View filing
Jul 17, 2026—4PRIMARY DOCUMENTJul 15, 20260000874015-26-000245View filing
Jul 17, 2026—4PRIMARY DOCUMENTJul 15, 20260000874015-26-000244View filing
Jul 10, 2026—8-K8-KJul 9, 20260001140361-26-028154View filing
Jul 9, 2026—4PRIMARY DOCUMENTJul 7, 20260000874015-26-000239View filing
Jul 9, 2026—4PRIMARY DOCUMENTJul 7, 20260000874015-26-000237View filing
Jul 9, 2026—4PRIMARY DOCUMENTJul 7, 20260000874015-26-000236View filing
Jul 9, 2026—8-K8-KJul 9, 20260001140361-26-028092View filing
Jul 7, 2026—144——0001972481-26-000227View filing
Jul 7, 2026—144——0001972481-26-000226View filing
Jul 7, 2026—144——0001972481-26-000225View filing
Jul 6, 2026—4PRIMARY DOCUMENTJul 1, 20260000874015-26-000227View filing
Jul 6, 2026—4PRIMARY DOCUMENTJul 1, 20260000874015-26-000226View filing
Jul 6, 2026—4PRIMARY DOCUMENTJul 1, 20260000874015-26-000228View filing
Jul 6, 2026—4PRIMARY DOCUMENTJul 1, 20260000874015-26-000232View filing
Jul 6, 2026—4PRIMARY DOCUMENTJul 1, 20260000874015-26-000231View filing
Quarterly and monthly research
PeriodResearch summary
Jun 30, 2026Derived quarterly snapshot; AI narrative pending
Jun 30, 2026Latest reported fundamentals for fiscal period FY-2026-Q2. Revenue: $267949000. Revenue growth: -40.73%. EPS: $-0.690. EPS growth: -198.57%. Gross margin: 0.00%. Operating margin: -38.18%. Net margin: -42.79%. Free cash flow: $549451000.
MonthResearch summary
Oct 1, 2026Derived monthly snapshot; AI narrative pending
Third-party metrics and ratios

Showing up to 40 recent metric records and 40 ratio records from the query window. Provider periods, units and validity flags are preserved when available.

PeriodReport periodFiscal yearQuarterPeriod typeCategoryValueUnitCurrencyValidSource
Jun 30, 2026Jun 30, 202620262instantcommon_stock166,000—USDYes3Spread
Jun 30, 2026Jun 30, 202620262instantconvertible_notes1,322,611,000—USDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualfx_effect-188,000—USDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualinterest_paid5,212,000—USDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualother_operating_activities-21,906,000—USDYes3Spread
Jun 30, 2026Jun 30, 202620262instantaccounts_payable47,704,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantaccounts_receivable_net58,845,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualaccrued_capital_expenditures1,042,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantaccrued_compensation_and_benefits50,293,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantaccrued_expenses115,778,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantaccumulated_other_comprehensive_income-33,897,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualacquisitions_net_of_cash-3,640,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantadditional_paid_in_capital3,311,837,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualamortization_of_debt_costs29,155,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualcapital_expenditures-37,843,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantcash_and_equivalents350,065,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualcash_beginning_of_period372,260,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualcash_end_of_period350,065,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualchange_in_accounts_payable18,583,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualchange_in_accrued_compensation-65,943,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualchange_in_accrued_liabilities12,851,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualchange_in_deferred_revenue-28,895,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualchange_in_income_taxes164,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualchange_in_inventory-24,626,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualchange_in_other_assets-38,265,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualchange_in_receivables7,214,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualcost_of_revenue-5,721,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantcurrent_assets2,491,274,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantcurrent_liabilities315,638,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantdeferred_revenue_current73,837,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantdeferred_revenue_noncurrent63,030,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualdepreciation_and_amortization8,095,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualeps_basic-1.25USD/shareUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualeps_diluted-1.25USD/shareUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualgain_loss_on_investments12,401,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualincome_before_taxes-205,692,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262semiannualincome_taxes_paid1,200,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantincome_taxes_payable2,877,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantinventory50,833,000USDUSDYes3Spread
Jun 30, 2026Jun 30, 202620262instantlease_liability_noncurrent262,476,000USDUSDYes3Spread
PeriodReport periodFiscal yearQuarterPeriod typeRatio categoryRatioValuePercentileMissing inputsValidSource
Jun 30, 2026Jun 30, 202620262quarterlyprofitabilitygross_margin_pct0+0.00%gross_profitNo3Spread
Jun 30, 2026Jun 30, 202620262quarterlyefficiencyasset_turnover0.09+21.64%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyliquiditycash_ratio1.11+83.00%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlycash_flowcf_margin_pct211.06+99.03%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlycash_flowcf_to_net_income-4.93+2.81%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyliquiditycurrent_ratio7.89+93.58%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyleveragedebt_to_assets0.85+81.63%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlysectordebt_to_ebitda-26.03+8.48%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyleveragedebt_to_equity5.81+94.54%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlysectorebitda_margin_pct-36.63+5.83%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyleverageequity_multiplier6.81+94.46%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlycash_flowfree_cash_flow549,451,000+87.60%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyleverageinterest_coverage-22.15+7.51%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyefficiencyinventory_turnover0.05+0.73%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyprofitabilitynet_margin_pct-42.79+9.11%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlycash_flowoperating_cf_ratio1.79+98.25%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyprofitabilityoperating_margin_pct-38.18+7.95%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyliquidityquick_ratio7.73+93.85%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyefficiencyreceivables_turnover4.55+80.74%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyprofitabilityroa_pct-3.83+15.79%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyprofitabilityroe_pct-26.07+4.20%—Yes3Spread
Jun 30, 2026Jun 30, 202620262quarterlyliquidityworking_capital2,175,636,000+87.50%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlyprofitabilitygross_margin_pct0+0.00%gross_profitNo3Spread
Mar 31, 2026Mar 31, 202620261quarterlyefficiencyreceivables_turnover0+0.00%receivablesNo3Spread
Mar 31, 2026Mar 31, 202620261quarterlyefficiencyasset_turnover0.09+22.26%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlyliquiditycash_ratio0.24+42.46%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlycash_flowcf_margin_pct-322.17+2.59%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlycash_flowcf_to_net_income8.57+96.06%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlyliquiditycurrent_ratio4.1+86.94%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlyleveragedebt_to_assets1.27+89.13%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlysectordebt_to_ebitda-31.65+5.20%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlyleveragedebt_to_equity7.31+95.42%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlysectorebitda_margin_pct-46.11+7.09%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlyleverageequity_multiplier5.73+91.54%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlycash_flowfree_cash_flow-814,582,000+2.33%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlyleverageinterest_coverage-22.76+7.40%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlyefficiencyinventory_turnover0.54+13.04%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlyprofitabilitynet_margin_pct-37.6+10.22%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlycash_flowoperating_cf_ratio-1.11+4.34%—Yes3Spread
Mar 31, 2026Mar 31, 202620261quarterlyprofitabilityoperating_margin_pct-47.72+9.34%—Yes3Spread
Data quality and provenance

This page does not fill gaps with sample data. Values shown above come from the connected market-data and research tables.

No verified records available for this section yet.
RetrievedDatasetProviderStatus
Oct 8, 2026company_profileUS Market AI / SEC-mapped universeVerified
Identifiers and model evaluation
IdentifierValueSource
cik874015stocks.cik
tickerIONSstocks.symbol
No verified records available for this section yet.
QUICK ANSWERS

Frequently asked questions

What is IONS stock's current price?

The latest stored quote for IONS is 44.38. The quote timestamp is 10/19/2026, 4:00:00 AM. Prices can change during market hours.

What is the IONS stock forecast and analysis?

The latest available quantitative model signal is “neutral”. Review the forecast horizons alongside the company's reported financials, valuation, technical indicators and risks below; model outputs are estimates, not guarantees or personalized investment advice.

What is the IONS stock price target?

The forecast table shows stored quantitative model outputs for the available horizons. These are model targets, not necessarily Wall Street analyst consensus; a verified consensus target is not assumed unless explicitly stored.

What is the IONS stock price prediction for 2030?

A stored long-term model scenario for 2030 is shown in the forecast table. Long-range scenarios are highly uncertain and should be reviewed alongside the model version and assumptions.

What are the bullish and bearish views on IONS?

A sufficiently detailed analyst-opinion dataset is not currently stored for this stock. The bull and bear cases on this page are conditional evidence-based scenarios, not attributed analyst recommendations.

What is the IONS stock price prediction for 2026?

A verified 2026 long-term model output is not currently stored for this stock. Check the forecast section for available horizons rather than relying on an unsupported target.

Is IONS stock overvalued or undervalued?

The latest stored trailing P/E is 23.83. Those multiples alone cannot establish fair value; compare growth, cash flow, earnings quality, risk and relevant peers.

What is IONS's P/E ratio?

The latest stored trailing P/E ratio is 23.83. P/E compares share price with earnings per share and should be interpreted alongside growth, cyclicality and accounting quality.

What is IONS's 52-week high and low?

The stored 52-week range is 42.08 to 86.74. This describes the recent trading range, not a forecast or a guaranteed support/resistance level.

Does IONS pay a dividend, and what is its dividend history?

No dividend records are currently stored for this stock. That absence does not prove the company pays no dividend.

When is IONS's next earnings report?

The latest SEC filing/observation date in this database is Jul 29, 2026. This is not a verified earnings announcement date or a confirmed next-report date; check company investor relations for the official calendar.

How has IONS stock performed recently?

The price chart uses 250 stored daily observations, and the market snapshot includes the latest available quote. Use the chart to inspect the period shown; past performance does not predict future returns.

Is IONS stock in a bullish or bearish trend?

The stored technical snapshot classifies the trend as “bearish”. This rule-based label is based on available indicators and is not a standalone buy or sell signal.

What are the main risks of investing in IONS?

Available risk metrics are shown in the risk and performance section. These metrics do not capture every business, competitive, regulatory or market risk; review company filings and disclosures as well.

Where can I find IONS's financial statements and earnings history?

Use the Financial Statements section for stored statement records, financial metric history, earnings results and estimate revisions. Coverage depends on the data available for this company.

Does US Market AI provide a guaranteed IONS price target?

No. Forecasts shown here are quantitative model outputs, not guarantees or personalized financial advice. Missing forecast values are left unavailable rather than filled with invented targets.

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US MARKET AI · STOCK RESEARCH

Data availability varies by company and provider. Missing values are omitted rather than estimated. Forecasts are model outputs and should be independently evaluated.

Research updated Oct 19, 2026 · Research methodology · Disclaimer